Bluebird has pitched Zynteglo as a potential one-time treatment that could do away with the need for transfusions, resulting in savings for patients over the long term. The average cost of transfusions over the lifetime can be $6.4 million, Chief Operating Officer Tom Klima told Reuters before the approval. “We feel the prices we are considering still bring a significant value to patients.” Bluebird has been in talks with insurers about a one-time payment option. “Potentially, up to 80% of that payment will be reimbursed if a patient does not achieve transfusion independence, they (insurers) are very excited about that,” Klima said. The FDA warned of a potential risk of blood cancer with the treatment but noted studies had no such cases. “Bluebird expects to start the treatment process for patients in the fourth quarter,” reports Reuters. “No revenue is, however, expected from the therapy in 2022 as the treatment cycle would take an average of 70 to 90 days from initial cell collection to final transfusion.”
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